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Dr Andrew KleinDr Andrew A Klein

Consultant Anaesthetist

Contact Details
Switchboard 01480 830541
Fax 01480 831315

Melanie E J Yea
Tel: 01480 364406 / 01480 36438

Cardiothoracic anaesthesia and intensive care.

Specialist Clinical Interests
Blood transfusion. Transoesophageal echocardiography.

Research Interests
Blood conservation and cell salvage.

Education and Training

Current membership(s) of professional, national and regional bodies and university posts
Royal College of Anaesthetists, Association of Cardiothoracic Anaesthetists, Society of Cardiovascular Anesthesiologists, British society of echocardiography.
Dr Klein is Editor-in-Chief of the journal Anaesthesia, a council member of the Association of Cardiothoracic Anaesthetists (ACTA UK), and an examiner for the Royal College of Anaesthetists.
He is also a Fellow of Murray Edwards College, University of Cambridge, and their tutor/lecturer in Pharmacology.

Recent and Important Publications

Ortmann E, Besser MW, Klein aa. Antifibrinolytic agents in current anaesthetic practice. British Journal of Anaesthesia 2013

Jones NL, Edmonds L, Ghosh S, Klein AA. A review of enhanced recovery for thoracic anaesthesia and surgery. Anaesthesia 2013; 68: 179-189.

Ortmann E, Klein AA, Sharples LD, et al. Point-of-Care Assessment of Hypothermia and Protamine-Induced Platelet Dysfunction with Multiple Electrode Aggregometry (Multiplate®) in Patients Undergoing Cardiopulmonary Bypass. Anesthesia & Analgesia 2013; 116: 533-540.

S Ghosh, B Arthur, AA Klein. NICE guidance on CardioQTM oesophageal Doppler monitoring. Anaesthesia 2012; 66: 1081-1083.

Vuylsteke A, Sharples G, Klein A, et al. Circulatory arrest versus cerebral perfusion during pulmonary endarterectomy surgery (PEACOG): a randomised controlled trial. Lancet 2011; 378: 1379-97.
Hung M, Besser M, Sharples LD, Nair SR and Klein AA. The prevalence and association with transfusion, intensive care unit stay and mortality of pre-operative anaemia in a cohort of cardiac surgery patients. Anaesthesia 2011; 66: 212-8.
Besser MW and Klein AA. The coagulopathy of cardiopulmonary bypass. Critical reviews in clinical laboratory sciences 2011; 47: 197-212.

Reece MJ, Klein AA, Salviz EA, Hastings A, Ashworth A, Freeman C, Luddington RJ, Nair S and Besser MW. Near-patient platelet function testing in patients undergoing coronary artery surgery – a pilot study. Anaesthesia 2011; 66: 97-103.

Ashworth A and Klein A A. Cell salvage as part of a blood conservation strategy in anaesthesia. British Journal of Anaesthesia 2010; 105: 401-16.

Klein AA, Webb ST, Tsui S, Sudarshan C, Shapiro L and Densem C. Transcatheter aortic valve insertion: anaesthetic implications of emerging new technology. British Journal of Anaesthesia 2009 103: 792-99

Klein AA, Snell A, Nashef S A M, Hall R M O, Kneeshaw J D and Arrowsmith J E. The impact of intraoperative transoesophageal echocardiography on cardiac surgical practice. Anaesthesia 2009; 64: 947-52

Cardone D, Klein AA. Perioperative blood conservation. European Journal of Anaesthesia 2009; 26: 722-9
Klein AA, Nashef S A M, Sharples L, Bottrill F, Dyer M, Armstrong J, Vuylsteke A.. A randomized controlled trial of cell salvage in cardiac surgery. Anesthesia and Analgesia 2008; 107 (5): 1487-95.

A Snell, A. Klein, A Vuylsteke, R Hall, J Arrowsmith, M Berman, S Tsui and DP Jenkins. Successful extracorporeal membrane oxygenation (ECMO) support after pulmonary thromboendarterectomy.
Ann Thorac Surg 2008;86:1261–7.

Ghosh S, Klein AA, Prabhu M, Falter F, Arrowsmith JE. The Papworth BiVent tube: a feasibility study of a novel double lumen endotracheal tube and bronchial blocker in human cadavers. British Journal of Anaesthesia 2008; 101(3): 424-8



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